So, here's a few interesting facts about Peyton Manning in his career against the Browns in their expansion era. The Browns have held Manning to a 79.3 Passer rating, the lowest of any team in the NFL in his career and are the only team in the NFL who has forced Manning to throw more interceptions (7) than TD's (6) in his career.
All that totaled up has resulted in Manning having a 6-0 career record against the Browns. So do with all that what you will.